Description

1-[3-(2,3-Dihydro-1H-Indol-1-Ylsulfonyl)-4-Methoxyphenyl]Pyrrolidine-2,5-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its specific indole and pyrrolidine-2,5-dione (succinimide) core structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly those targeting neurological and inflammatory pathways. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and anti-inflammatory applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic scaffolds.
• Protease Inhibitor Development: The succinimide moiety suggests potential utility in the design of inhibitors for various enzymatic targets.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and protein function.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, non-commercial molecules for client research.

Basic Information

Product Name	1-[3-(2,3-Dihydro-1H-Indol-1-Ylsulfonyl)-4-Methoxyphenyl]Pyrrolidine-2,5-Dione
CAS No.	919683-21-9
Molecular Formula	C19H18N2O5S
Molecular Weight	386.42 g/mol
Synonyms	1-[3-(2,3-Dihydro-1H-indol-1-ylsulfonyl)-4-methoxyphenyl]pyrrolidine-2,5-dione; 1-[3-(Indolin-1-ylsulfonyl)-4-methoxyphenyl]pyrrolidine-2,5-dione; 1-(3-(Indoline-1-sulfonyl)-4-methoxyphenyl)pyrrolidine-2,5-dione; 1-(3-(2,3-Dihydro-1H-indol-1-ylsulfonyl)-4-methoxyphenyl)-2,5-pyrrolidinedione; 919683-21-9; 1-[3-(Indolin-1-Ylsulfonyl)-4-Methoxyphenyl]Succinimide
EINECS	Contact for details

Quality Control

Our 1-[3-(2,3-Dihydro-1H-Indol-1-Ylsulfonyl)-4-Methoxyphenyl]Pyrrolidine-2,5-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.