Description

1-tert-Butyl 2-Methyl 7-(Benzyloxy)-5-(tert-Butoxycarbonylamino)-4-Iodo-1H-Indole-1,2-Dicarboxylate is a sophisticated, multi-functional indole derivative designed for advanced synthetic chemistry. This compound serves as a critical, high-value pharmaceutical intermediate and building block for constructing complex molecules in drug discovery and development. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise, high-purity intermediates for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, cancer, and inflammation.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including cross-coupling reactions (e.g., Suzuki, Sonogashira) facilitated by the iodine substituent.
• Peptidomimetic Research: The tert-butoxycarbonyl (Boc) protected amino group makes it valuable for constructing indole-containing peptide analogs and peptidomimetics.
• Agrochemical Development: Serves as an intermediate in the research and production of advanced crop protection agents and pesticides.
• Material Science Research: Potential use in the development of organic electronic materials and functional dyes due to the conjugated indole core.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1-tert-Butyl 2-Methyl 7-(Benzyloxy)-5-(tert-Butoxycarbonylamino)-4-Iodo-1H-Indole-1,2-Dicarboxylate
CAS No.	919535-06-1
Molecular Formula	C27H31IN2O6
Molecular Weight	606.45 g/mol
Synonyms	1H-Indole-1,2-dicarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-iodo-7-(phenylmethoxy)-, 1-(1,1-dimethylethyl) 2-methyl ester; 5-(tert-Butoxycarbonylamino)-4-iodo-7-benzyloxyindole-1,2-dicarboxylic acid 1-tert-butyl 2-methyl ester; 4-Iodo-7-benzyloxy-5-Boc-aminoindole-1,2-dicarboxylic acid 1-tert-butyl 2-methyl ester; Boc-protected 4-iodo-7-benzyloxyindole-1,2-diester; 919535-06-1; tert-Butyl methyl 5-(Boc-amino)-4-iodo-7-(benzyloxy)-1H-indole-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Methyl 7-(Benzyloxy)-5-(tert-Butoxycarbonylamino)-4-Iodo-1H-Indole-1,2-Dicarboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.