Description

2-(4-Methylpiperazin-1-Yl)-4-Bromothiazole is a specialized heterocyclic organic compound featuring a bromothiazole core substituted with a methylpiperazine moiety. This molecular architecture makes it a valuable pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom.
• Agrochemical Development: Potential intermediate in the research and development of novel crop protection agents and fungicides.
• Material Science: Investigated as a monomer or precursor for advanced organic electronic materials and functional polymers.

Basic Information

Item	Details
Product Name	2-(4-Methylpiperazin-1-Yl)-4-Bromothiazole
CAS No.	919352-66-2
Molecular Formula	C8H12BrN3S
Molecular Weight	262.17 g/mol
Synonyms	4-Bromo-2-(4-methyl-1-piperazinyl)thiazole; 4-Bromo-2-(4-methylpiperazin-1-yl)thiazole; 2-(4-Methylpiperazin-1-yl)-4-bromothiazole; 919352-66-2; 4-Bromo-2-(N-methylpiperazinyl)thiazole; Thiazole, 4-bromo-2-(4-methyl-1-piperazinyl)-; 4-Bromo-2-(4-methylpiperazino)thiazole
EINECS	Contact for details

Quality Control

Our 2-(4-Methylpiperazin-1-Yl)-4-Bromothiazole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.