Description

2,2-Dimethyl-n-((5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methyl)Propan-1-Amine is a high-value, functionalized pyridine boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in its dual functionality, combining a protected boronic acid group for Suzuki-Miyaura cross-coupling reactions with a primary amine moiety for further derivatization, enabling the rapid construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, ligand synthesis, and the development of functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester group enables efficient, palladium-catalyzed carbon-carbon bond formation to create biaryl and heteroaryl structures.
• Ligand Synthesis: Used to prepare novel chelating ligands for catalysis, metal-organic frameworks (MOFs), and diagnostic imaging agents.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating specialty polymers, conductive materials, and organic electronic components.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes, activity-based protein profiling (ABPP) reagents, and bioconjugation linkers.

Basic Information

Product Name	2,2-Dimethyl-n-((5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methyl)Propan-1-Amine
CAS No.	919347-21-0
Molecular Formula	C17H29BN2O2
Molecular Weight	304.24 g/mol
Synonyms	1-Propanamine, 2,2-dimethyl-N-[[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]methyl]-; 3-((2,2-Dimethylpropylamino)methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(Aminomethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, N-tert-butyl derivative; 919347-21-0; Boronic acid, B-[5-[[(2,2-dimethylpropyl)amino]methyl]-3-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-n-((5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Methyl)Propan-1-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.