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1H-Indole-2,7-Diboronic Acid, Pinacol Ester CAS NO 919119-72-5


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CAS No.:919119-72-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1H-Indole-2,7-Diboronic Acid, Pinacol Ester is a high-purity, bifunctional boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, for the precise construction of complex organic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and advanced functional materials.

Application

  • Pharmaceutical Intermediate: A key synthon for constructing indole-based drug candidates, including kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with complex heterocyclic structures.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and host materials in display and lighting technologies.
  • Ligand and Catalyst Development: Employed in the synthesis of novel bidentate ligands for transition metal catalysis.
  • Polymer and Material Science: Facilitates the creation of conjugated polymers and organic semiconductors for electronic applications.
  • Chemical Biology Probes: Used to create tagged molecules for studying biological processes and protein interactions.

Basic Information

Item Details
Product Name 1H-Indole-2,7-Diboronic Acid, Pinacol Ester
CAS No. 919119-72-5
Molecular Formula C20H27B2NO4
Molecular Weight 367.06 g/mol
Synonyms 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 1H-Indole-2,7-diyldiboronic Acid Bis(pinacol) Ester; 2,7-Di(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; Indole-2,7-diboronic Acid Pinacol Ester; 2,7-Bis(Pinacolboranyl)-1H-Indole; 919119-72-5; 1H-Indole-2,7-diboronic acid pinacol ester
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Quality Control

Every batch of 1H-Indole-2,7-Diboronic Acid, Pinacol Ester is manufactured and tested under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all commercial quantities and are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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