Description

1H-Indole-4-Methanamine, 2,3-Dihydro- is a specialized indole derivative building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of complex, biologically active molecules. Pharmaceutical research and development teams, particularly those focused on central nervous system (CNS) agents and other therapeutic areas, are the primary industrial users of this high-value chemical.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its complex heterocyclic structure.
• Chemical Biology & Proteomics: Serves as a scaffold or labeling agent in the study of protein interactions and enzyme function.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or photophysical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Item	Detail
Product Name	1H-Indole-4-Methanamine, 2,3-Dihydro-
CAS No.	918864-94-5
Molecular Formula	C9H12N2
Molecular Weight	148.21 g/mol
Synonyms	2,3-Dihydro-1H-indole-4-methanamine; 4-(Aminomethyl)-2,3-dihydro-1H-indole; 1H-Indole-4-methanamine, 2,3-dihydro-; 2,3-Dihydroindole-4-methylamine; 4-Aminomethyl-2,3-dihydroindole; (2,3-Dihydro-1H-indol-4-yl)methanamine; 4-(Aminomethyl)indoline
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-4-Methanamine, 2,3-Dihydro- adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.