Description

2-Bromoethyl-D4-Amine Hbr is a deuterium-labeled analog of 2-bromoethylamine hydrobromide, serving as a crucial stable isotope-labeled building block for advanced research and development. Its primary value lies in enabling precise metabolic, pharmacokinetic, and mechanistic studies through mass spectrometry and NMR techniques, where it acts as an internal standard or tracer. This high-purity intermediate is essential for pharmaceutical, agrochemical, and academic researchers focused on synthesizing and analyzing novel compounds, particularly in the fields of medicinal chemistry and drug discovery.

Application

• Pharmaceutical Research & Development: Used as a deuterium-labeled intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for metabolic fate and stability studies.
• Mass Spectrometry Internal Standards: Serves as a critical internal standard for the accurate quantification of its non-deuterated counterpart or related metabolites in bioanalytical assays (LC-MS/MS).
• Mechanistic & Pathway Studies: Employed as a tracer to elucidate biochemical pathways and reaction mechanisms in both in vitro and in vivo systems.
• Agrochemical Development: Utilized in the synthesis of labeled agrochemicals to study environmental fate, degradation, and uptake in plants.
• NMR Spectroscopy: Acts as a useful probe in nuclear magnetic resonance studies due to the distinct spectroscopic signature of deuterium atoms.
• Chemical Biology Probes: Incorporated into molecular probes to track and study biological interactions and processes with high specificity.

Basic Information

Product Name	2-Bromoethyl-D4-Amine Hbr
CAS No.	918633-70-2
Molecular Formula	C2D4Br2N • HBr (or C2HD4BrN • HBr)
Molecular Weight	Contact for details
Synonyms	2-Bromoethyl-d4-amine hydrobromide; 2-Aminoethyl-d4 bromide hydrobromide; Deutero-2-bromoethylamine HBr; (2-Bromoethyl-1,1,2,2-d4)amine hydrobromide; Ethyl-1,1,2,2-d4-amine, 2-bromo-, hydrobromide; 1-Amino-2-bromoethane-d4 hydrobromide; Deuterated 2-Bromoethylamine HBr; Bromoethylamine-d4 HBr
EINECS	Contact for details

Quality Control

Every batch of 2-Bromoethyl-D4-Amine Hbr is manufactured and tested under strict quality management protocols to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment (D%, typically >98 atom % D), chemical purity, and specific tests are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.