Description

3-(1,2,3,6-Tetrahydro-4-Pyridinyl)-1H-Indole-6-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• Neurological & Psychiatric Drug Development: Particularly relevant for the synthesis of compounds targeting serotonin and dopamine receptor pathways.
• Preclinical & Clinical Trial Material Production: Supplied for the synthesis of compounds required for non-clinical studies and early-phase clinical trials.
• Custom Synthesis & Contract Manufacturing: Provided to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	3-(1,2,3,6-Tetrahydro-4-Pyridinyl)-1H-Indole-6-Carbonitrile
CAS No.	918525-20-9
Molecular Formula	C14H13N3
Molecular Weight	223.28 g/mol
Synonyms	6-Cyano-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; 3-(1,2,3,6-Tetrahydro-4-pyridinyl)-1H-indole-6-carbonitrile; 1H-Indole-6-carbonitrile, 3-(1,2,3,6-tetrahydro-4-pyridinyl)-; Tetrahydro-4-pyridinyl indole carbonitrile; 918525-20-9; 3-(1,2,3,6-Tetrahydro-pyridin-4-yl)-1H-indole-6-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-(1,2,3,6-Tetrahydro-4-Pyridinyl)-1H-Indole-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.