Description

7-Chloro-6-Fluoroisoquinoline is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, offering precise reactivity for introducing the isoquinoline scaffold with halogen handles for further functionalization. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides with enhanced activity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology: Employed as a probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	7-Chloro-6-Fluoroisoquinoline
CAS No.	918490-51-4
Molecular Formula	C9H5ClFN
Molecular Weight	181.60 g/mol
Synonyms	6-Fluoro-7-chloroisoquinoline; Isoquinoline, 7-chloro-6-fluoro-; 7-Chloro-6-fluoro-isoquinoline; 918490-51-4; 7-Chloro-6-fluoroisoquinoline; 6-Fluoro-7-chloro-isoquinoline
EINECS	Contact for details

Quality Control

Our 7-Chloro-6-Fluoroisoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.