Description

2-Bromo-1-Chloro-4-(Methylsulfonyl)Benzene is a high-purity, multi-functional halogenated aromatic sulfone building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, chlorine, and a methylsulfonyl group on a benzene ring, makes it a versatile and valuable intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aryl sulfone moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the sulfone group can enhance biological activity.
• Material Science Research: Serves as a building block for novel polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing sulfone group.
• Cross-Coupling Reactions: The bromine and chlorine atoms provide distinct sites for selective palladium-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig couplings.
• Chemical Library Development: Employed in medicinal and combinatorial chemistry for the rapid generation of diverse compound libraries for screening.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Bromo-1-Chloro-4-(Methylsulfonyl)Benzene
CAS No.	918350-18-2
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	1-Bromo-2-Chloro-4-(Methylsulfonyl)Benzene; 4-Bromo-3-Chlorophenyl Methyl Sulfone; 2-Chloro-1-Bromo-4-Methylsulfonylbenzene; 3-Chloro-4-Bromophenyl Methyl Sulfone; Methyl 3-Chloro-4-Bromophenyl Sulfone; 918350-18-2; (2-Chloro-4-bromophenyl)(methyl)sulfone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Chloro-4-(Methylsulfonyl)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.