Description

2-Chloroethynylbenzene is a versatile halogenated aromatic alkyne building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a reactive chloro substituent and an ethynyl group, makes it a critical precursor for constructing complex molecular architectures. This high-value intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its reactivity to create novel bioactive compounds.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced materials with tailored properties.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organometallic complexes.
• Organic Electronic Materials: A precursor in the synthesis of conjugated molecules and polymers for applications in OLEDs, OFETs, and other electronic devices.
• Chemical Research & Development: A valuable reagent for Sonogashira coupling and other palladium-catalyzed cross-coupling reactions in academic and industrial R&D settings.

Basic Information

Product Name	2-Chloroethynylbenzene
CAS No.	1483-82-5
Molecular Formula	C8H5Cl
Molecular Weight	136.58 g/mol
Synonyms	1-Chloro-2-ethynylbenzene; o-Chlorophenylacetylene; 2-Ethynylchlorobenzene; (2-Chlorophenyl)acetylene; 2-Chlorophenylacetylene; o-Ethynylchlorobenzene; Benzene, 1-chloro-2-ethynyl-
EINECS	Contact for details

Quality Control

Our 2-Chloroethynylbenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including GC, HPLC, and NMR analysis, to verify identity and purity. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.