Description

1,3-Bis(Bromomethyl)-5-Methoxybenzene is a versatile brominated aromatic building block of significant importance in advanced organic synthesis. Its bifunctional reactivity, featuring two bromomethyl groups, makes it a critical precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Key intermediate in the synthesis of pharmaceutical active ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Precursor for the preparation of macrocyclic compounds and cryptands used in supramolecular chemistry and catalysis.
• Building block for the development of novel polymers and advanced materials with specific functional properties.
• Starting material in the synthesis of ligands for metal-organic frameworks (MOFs) and other coordination polymers.
• Intermediate in agrochemical research for creating new active molecules with herbicidal or insecticidal properties.
• Useful reagent in cross-coupling reactions and nucleophilic substitution reactions to introduce the dimethoxybenzene scaffold.

Basic Information

Product Name	1,3-Bis(Bromomethyl)-5-Methoxybenzene
CAS No.	19254-79-6
Molecular Formula	C10H10Br2O
Molecular Weight	307.99 g/mol
Synonyms	5-Methoxy-1,3-bis(bromomethyl)benzene; 1,3-Bis(bromomethyl)-5-methoxybenzene; 3,5-Bis(bromomethyl)anisole; 5-Methoxy-m-xylene-α,α'-dibromide; α,α'-Dibromo-5-methoxy-m-xylene; 1,3-Di(bromomethyl)-5-methoxybenzene; 3,5-Dibromomethylanisole
EINECS	Contact for details

Quality Control

Our 1,3-Bis(Bromomethyl)-5-Methoxybenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.