Description

1-(2-Bromopyridin-4-Yl)Ethanone Hydrobromide is a high-purity organic salt, serving as a critical brominated pyridine derivative and versatile building block in advanced chemical synthesis. Its value lies in providing a reactive ketone functionality adjacent to a halogenated heterocycle, enabling precise molecular construction for complex targets. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and the development of biochemical probes.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	1-(2-Bromopyridin-4-Yl)Ethanone Hydrobromide
CAS No.	918142-93-5
Molecular Formula	C7H7Br2NO
Molecular Weight	296.95 g/mol
Synonyms	2-Bromo-4-acetylpyridine Hydrobromide; 1-(2-Bromo-4-pyridinyl)ethanone Hydrobromide; 4-Acetyl-2-bromopyridine Hydrobromide; 2-Bromo-4-pyridyl methyl ketone Hydrobromide; Ethanone, 1-(2-bromo-4-pyridinyl)-, hydrobromide; 2-Bromo-4-pyridinecarbonylmethane Hydrobromide
EINECS	Contact for details

Quality Control

Our 1-(2-Bromopyridin-4-Yl)Ethanone Hydrobromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.