Description

Rac-4-(6-Chloro-2-Oxo-2,3-Dihydro-1H-Indol-3-Yl)-Piperidine-1-Carboxylic Acid tert-Butyl is a high-purity, advanced pharmaceutical intermediate featuring a complex indole-piperidine hybrid structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new drug candidates, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient production of target active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Custom Synthesis Building Block: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	Rac-4-(6-Chloro-2-Oxo-2,3-Dihydro-1H-Indol-3-Yl)-Piperidine-1-Carboxylic Acid tert-Butyl
CAS No.	917917-50-1
Molecular Formula	C18H23ClN2O3
Molecular Weight	350.84 g/mol
Synonyms	4-(6-Chloro-2-oxo-2,3-dihydro-1H-indol-3-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(6-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl)piperidine-1-carboxylate; 1-Boc-4-(6-chloro-2-oxoindolin-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(6-chloro-2-oxo-2,3-dihydro-1H-indol-3-yl)piperidine; 917917-50-1; Rac-4-(6-Chloro-2-Oxoindolin-3-Yl)-1-N-Boc-piperidine
EINECS	Contact for details

Quality Control

Our Rac-4-(6-Chloro-2-Oxo-2,3-Dihydro-1H-Indol-3-Yl)-Piperidine-1-Carboxylic Acid tert-Butyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.