Description

2-(2-Amino-4-(Trifluoromethyl)Phenyl)-2H-Isoindole-1-Carbonitrile is a specialized organic compound featuring a unique isoindole core substituted with an amino-trifluoromethylphenyl group and a nitrile functionality. This molecular architecture makes it a high-value intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical research and agrochemical development. It is primarily needed by R&D chemists and process development scientists in the life sciences sector seeking to incorporate its distinct trifluoromethyl and fused-ring pharmacophores into new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for targets in oncology, CNS disorders, and inflammation.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical entity.

Basic Information

Product Name	2-(2-Amino-4-(Trifluoromethyl)Phenyl)-2H-Isoindole-1-Carbonitrile
CAS No.	917607-75-1
Molecular Formula	C16H10F3N3
Molecular Weight	301.27 g/mol
Synonyms	2-[2-Amino-4-(trifluoromethyl)phenyl]-2H-isoindole-1-carbonitrile; 2-(2-Amino-4-trifluoromethylphenyl)-2H-isoindole-1-carbonitrile; 1-Cyano-2-[2-amino-4-(trifluoromethyl)phenyl]isoindole; 2H-Isoindole-1-carbonitrile, 2-[2-amino-4-(trifluoromethyl)phenyl]-; 917607-75-1; AI3-73031; CTK8I8069
EINECS	Contact for details

Quality Control

Our 2-(2-Amino-4-(Trifluoromethyl)Phenyl)-2H-Isoindole-1-Carbonitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.