Description

5-Boc-Aminoindazole is a high-purity, protected indazole derivative used as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and the development of novel pharmaceutical agents, particularly in kinase inhibitor programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the research and development of protein kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Peptidomimetic Synthesis: Employed in the construction of peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Useful for creating tool compounds to study biological processes and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	5-Boc-Aminoindazole
CAS No.	917474-59-0
Molecular Formula	C₁₂H₁₅N₃O₂
Molecular Weight	233.27 g/mol
Synonyms	1H-Indazol-5-amine, N-BOC-; tert-Butyl (1H-indazol-5-yl)carbamate; 5-[(tert-Butoxycarbonyl)amino]-1H-indazole; 5-(Boc-amino)indazole; N-Boc-5-aminoindazole; 5-Amino-1H-indazole-1-carboxylic acid tert-butyl ester; Boc-5-Aminoindazole
EINECS	Contact for details

Quality Control

Our 5-Boc-Aminoindazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.