Description

1H-Indole, 5-Bromo-2,3-Dihydro-2-Methyl-, (2R)- is a high-purity, single-enantiomer indole derivative, a crucial chiral building block for advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized indole core, enabling the precise construction of complex molecules with targeted biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, especially for central nervous system (CNS) targets and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the specific stereochemistry can influence efficacy and environmental profile.
• Asymmetric Catalysis Research: Serves as a sophisticated ligand precursor or substrate in the development of new catalytic systems for enantioselective synthesis.
• Material Science: Potential building block for specialty polymers and organic electronic materials due to the indole moiety's electronic properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1H-Indole, 5-Bromo-2,3-Dihydro-2-Methyl-, (2R)-
CAS No.	916903-14-5
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	(2R)-5-Bromo-2-methyl-2,3-dihydro-1H-indole; (R)-5-Bromo-2-methylindoline; (R)-5-Bromo-2-methyl-2,3-dihydro-1H-indole; 5-Bromo-2-methylindoline, (R)-; 1H-Indole, 5-bromo-2,3-dihydro-2-methyl-, (2R)-; (R)-5-Bromo-2-methyl-2,3-dihydroindole; (2R)-5-Bromo-2-methylindoline
EINECS	Contact for details

Quality Control

Our production of (2R)-5-Bromo-2-methyl-2,3-dihydro-1H-indole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC/MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), enantiomeric excess (ee), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please inquire.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.