Description

trans-1,1-Dioxo-4-Prop-2-Ynylamino-Tetrahydrothiophen-3-Ol Hydrochloride is a high-purity, synthetic organic compound primarily used as a key intermediate in advanced pharmaceutical research and development. This compound is valued for its specific molecular architecture, which makes it a crucial building block in the synthesis of novel therapeutic agents, particularly in targeted drug discovery programs. It is essential for research chemists and process development scientists working in medicinal chemistry, especially within the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery and development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new chemical entities targeting specific biological pathways.
• Process Chemistry: Serves as a key starting material or intermediate in the scale-up and optimization of synthetic routes for potential drug candidates.
• Bioconjugation & Probe Development: The propynylamino group can be utilized in click chemistry reactions for labeling, bioconjugation, or creating molecular probes.
• Academic & Institutional Research: Employed in university and research institute laboratories for exploratory synthetic projects and methodological studies.

Basic Information

Item	Details
Product Name	trans-1,1-Dioxo-4-Prop-2-Ynylamino-Tetrahydrothiophen-3-Ol Hydrochloride
CAS No.	916901-10-5
Molecular Formula	C7H10ClNO4S
Molecular Weight	239.68 g/mol
Synonyms	4-(Prop-2-yn-1-ylamino)tetrahydro-3-hydroxy-1,1-dioxothiophene hydrochloride; 3-Hydroxy-4-(2-propynylamino)tetrahydrothiophene 1,1-dioxide hydrochloride; Tetrahydro-3-hydroxy-4-[(2-propynyl)amino]-1,1-dioxothiophene hydrochloride; trans-4-(Prop-2-ynylamino)tetrahydrothiophene-3-ol 1,1-dioxide hydrochloride
EINECS	Contact for details

Quality Control

Our trans-1,1-Dioxo-4-Prop-2-Ynylamino-Tetrahydrothiophen-3-Ol Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.