Description

2-(4-(2-(Trifluoromethyl)Benzoyl)Piperazin-1-Yl)Thiazole-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethyl-benzoyl-piperazine-thiazole carboxamide structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drug candidates, leveraging its unique properties for enhanced bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a specialized scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: Potential building block for compounds targeting various protease enzymes, relevant in virology and oncology research.
• Kinase Inhibitor Development: Applied in the synthesis of molecules designed to modulate kinase activity for therapeutic applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic & Institutional Research: Utilized in university and institutional labs for exploratory pharmacology and chemical biology studies.

Basic Information

Product Name	2-(4-(2-(Trifluoromethyl)Benzoyl)Piperazin-1-Yl)Thiazole-5-Carboxamide
CAS No.	916888-66-9
Molecular Formula	C16H15F3N4O2S
Molecular Weight	384.38 g/mol
Synonyms	2-[4-[2-(Trifluoromethyl)benzoyl]piperazin-1-yl]-1,3-thiazole-5-carboxamide; 2-(4-(2-(Trifluoromethyl)benzoyl)piperazin-1-yl)thiazole-5-carboxamide; 916888-66-9; Thiazole-5-carboxamide, 2-[4-[2-(trifluoromethyl)benzoyl]-1-piperazinyl]-; 2-(4-(2-(Trifluoromethyl)benzoyl)piperazin-1-yl)-1,3-thiazole-5-carboxamide
EINECS	Contact for details

Quality Control

Our 2-(4-(2-(Trifluoromethyl)Benzoyl)Piperazin-1-Yl)Thiazole-5-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.