Description

4-Cyanothiophen-2-Boronic Acid Pinacol Ester is a high-value organoboron building block essential for modern cross-coupling chemistry, particularly Suzuki-Miyaura reactions. Its unique structure, featuring both a cyano electron-withdrawing group and a protected boronic acid moiety, enables the efficient synthesis of complex, functionalized heterocyclic scaffolds. This compound is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing functionalized thiophene cores for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science Research: Serves as a precursor for creating conjugated polymers and organic electronic materials for use in OLEDs, sensors, and semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and ligands for studying biological targets and pathways.
• Catalyst & Ligand Development: A valuable starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring advanced boronic ester chemistry.

Basic Information

Product Name	4-Cyanothiophen-2-Boronic Acid Pinacol Ester
CAS No.	916454-59-6
Molecular Formula	C11H14BNO2S
Molecular Weight	235.11 g/mol
Synonyms	2-(4-Cyanothiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Cyanothiophene-2-boronic acid pinacol ester; 2-(4-Cyanothiophen-2-yl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 4-Cyano-2-thienylboronic acid pinacol ester; 4-Cyanothiophen-2-ylboronic acid pinacol ester; Pinacol 4-cyanothiophene-2-boronate; 916454-59-6
EINECS	Contact for details

Quality Control

Our 4-Cyanothiophen-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) are available for every batch upon request, supporting compliance with rigorous industry and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.