Description

5-(Chloromethyl)-2-(2-Methylphenyl)-1,3-Thiazole Hydrochloride is a high-purity, functionalized thiazole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce the versatile 1,3-thiazole moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobial compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its reactive chloromethyl group and aromatic structure.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeled compounds for studying biological pathways and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Item	Details
Product Name	5-(Chloromethyl)-2-(2-Methylphenyl)-1,3-Thiazole Hydrochloride
CAS No.	915922-47-3
Molecular Formula	C11H11Cl2NS
Molecular Weight	268.18 g/mol
Synonyms	2-(2-Methylphenyl)-5-(chloromethyl)-1,3-thiazole hydrochloride; 5-(Chloromethyl)-2-(o-tolyl)-1,3-thiazole hydrochloride; 2-(2-Methylphenyl)-5-(chloromethyl)thiazole HCl; 1,3-Thiazole, 5-(chloromethyl)-2-(2-methylphenyl)-, hydrochloride; o-Tolyl-5-chloromethylthiazole hydrochloride
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)-2-(2-Methylphenyl)-1,3-Thiazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.