Description

5-Indolyl tert-Butyl Carbonate is a specialized indole derivative used as a key synthetic intermediate in advanced organic synthesis. This compound is valued for its role in protecting the indole nitrogen, enabling selective functionalization in complex molecule construction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug candidates, particularly those containing indole or tryptamine cores.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that leverage indole chemistry for biological activity.
• Organic Synthesis Research: Serves as a protected indole precursor in academic and industrial R&D for constructing complex heterocyclic frameworks.
• Peptide & Alkaloid Chemistry: Employed in the synthesis of indole-containing natural products, peptides, and alkaloids where selective nitrogen protection is required.
• Material Science Precursor: Investigated as a monomer or intermediate for synthesizing specialized polymers and advanced organic materials.

Basic Information

Product Name	5-Indolyl tert-Butyl Carbonate
CAS No.	915207-97-5
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	1H-Indol-5-yl tert-butyl carbonate; 5-(tert-Butoxycarbonyloxy)indole; tert-Butyl 5-indolyl carbonate; 5-Indolyl tert-butyl carbonate; Boc-5-indolol; 5-Hydroxyindole tert-butyl carbonate; N-Boc-5-hydroxyindole; 5-(Boc-oxy)indole
EINECS	Contact for details

Quality Control

Our 5-Indolyl tert-Butyl Carbonate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.