Description

5-Carboxyindazole, Hcl is a high-purity, heterocyclic carboxylic acid derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical and agrochemical agents. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of complex molecules targeting various therapeutic areas. The material's specific reactivity profile makes it an essential intermediate for constructing indazole-based scaffolds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing the indazole core structure.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for developing new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Material Science: Potential intermediate for the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process development for third-party clients.

Basic Information

Product Name	5-Carboxyindazole, Hcl
CAS No.	915139-44-5
Molecular Formula	C8H7N2O2 • HCl
Molecular Weight	200.61 g/mol (Free base: 163.15 g/mol)
Synonyms	1H-Indazole-5-carboxylic acid hydrochloride; 5-Indazolecarboxylic acid hydrochloride; 5-Carboxy-1H-indazole HCl; Indazole-5-carboxylic acid HCl; 1H-Indazole-5-carboxylic acid HCl salt; 5-CIA HCl; 5-Carboxyindazole hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Carboxyindazole, Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.