Description

2-(3-Bromophenyl)-2,2-Difluoro-Ethanol is a high-value organofluorine building block characterized by its bromophenyl and difluoroethanol functional groups. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. It serves as a key intermediate for researchers and manufacturers in fine chemical, pharmaceutical R&D, and material science sectors seeking to incorporate complex fluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorinated structure can enhance efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromophenyl moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex biaryl structures.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new fluorination methodologies and the properties of fluorinated compounds.
• Polymer Modification: Can be used to introduce fluorinated side chains into polymers to alter surface properties, such as hydrophobicity and chemical resistance.

Basic Information

Product Name	2-(3-Bromophenyl)-2,2-Difluoro-Ethanol
CAS No.	915133-40-3
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04 g/mol
Synonyms	2-(3-Bromophenyl)-2,2-difluoroethanol; 1-(3-Bromophenyl)-2,2-difluoroethan-1-ol; 3-Bromo-α,α-difluorobenzeneethanol; 2,2-Difluoro-2-(3-bromophenyl)ethanol; (3-Bromophenyl)difluoromethyl carbinol; α,α-Difluoro-m-bromobenzyl alcohol; 915133-40-3 (CAS)
EINECS	Contact for details

Quality Control

Our 2-(3-Bromophenyl)-2,2-Difluoro-Ethanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.