Description

3-Isoquinolinecarboxamide, n-[3,3-Bis(4-Fluorophenyl)Propyl]- is a high-purity, fluorinated organic compound of significant interest in advanced pharmaceutical research and development. Its unique molecular structure, featuring a fused isoquinoline core and bis(4-fluorophenyl)propyl side chain, makes it a valuable key intermediate for synthesizing novel active pharmaceutical ingredients (APIs). This compound is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in regulatory submissions.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Process Chemistry Development: Utilized for scaling up synthetic routes from laboratory to pilot plant scale for preclinical and clinical trial material production.
• Academic Research: Applied in university and institutional labs for investigating novel heterocyclic chemistry and fluorine-based bioisosteres.

Basic Information

Item	Details
Product Name	3-Isoquinolinecarboxamide, n-[3,3-Bis(4-Fluorophenyl)Propyl]-
CAS No.	914386-33-7
Molecular Formula	C25H20F2N2O
Molecular Weight	402.44 g/mol
Synonyms	N-[3,3-Bis(4-fluorophenyl)propyl]isoquinoline-3-carboxamide; 3-Isoquinolinecarboxamide, N-[3,3-bis(4-fluorophenyl)propyl]-; UNII-8Q4FYY6W9I; 8Q4FYY6W9I; BDBM50191057; ZINC000003869007; AKOS025310623; CHEMBL3185222
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxamide, n-[3,3-Bis(4-Fluorophenyl)Propyl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.