Description

3-Iodo-6-Methylindole-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists working on novel drug candidates, especially within oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of biologically active indole-based compounds and potential drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for targeted therapies.
• Chemical Synthesis: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce complex substituents.
• Agrochemical Development: Intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	3-Iodo-6-Methylindole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	914349-41-0
Molecular Formula	C14H16INO2
Molecular Weight	357.19 g/mol
Synonyms	tert-Butyl 3-iodo-6-methyl-1H-indole-1-carboxylate; 1H-Indole-1-carboxylic acid, 3-iodo-6-methyl-, 1,1-dimethylethyl ester; 3-Iodo-6-methyl-1H-indole-1-carboxylic acid tert-butyl ester; 6-Methyl-3-iodoindole-1-carboxylic acid tert-butyl ester; Boc-3-Iodo-6-methylindole; 3-Iodo-6-methylindole-1-Boc; 1-Boc-3-iodo-6-methylindole
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-Methylindole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.