Description

1-Boc-3-Bromo-7-Nitroindole is a high-purity, multi-functional indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of three distinct reactive sites—the Boc-protected amine, the bromine, and the nitro group—enabling precise, sequential functionalization for complex molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used to construct novel heterocyclic scaffolds for the development of new pesticides and herbicides.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, dyes, and photoactive polymers.
• Academic & R&D: A versatile reagent for methodological studies in cross-coupling reactions, palladium-catalyzed transformations, and protecting group chemistry.
• Peptidomimetics & Bioconjugation: The Boc-protected amine provides a handle for introducing indole-based motifs into peptides or for bioconjugation applications.

Basic Information

Product Name	1-Boc-3-Bromo-7-Nitroindole
CAS No.	914349-37-4
Molecular Formula	C₁₃H₁₃BrN₂O₄
Molecular Weight	341.16 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-bromo-7-nitroindole; tert-Butyl 3-bromo-7-nitro-1H-indole-1-carboxylate; 3-Bromo-7-nitro-1H-indole-1-carboxylic acid tert-butyl ester; 1-Boc-3-bromo-7-nitro-1H-indole; Boc-3-Br-7-NO₂-indole; 3-Bromo-7-nitroindole-1-carboxylic acid tert-butyl ester; 914349-37-4; tert-Butyl 3-bromo-7-nitroindole-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Bromo-7-Nitroindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical purity and structural integrity, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.