Description

n-Boc-3-Iodo-7-Methyl-Indole is a high-purity, protected indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is specifically engineered to facilitate the construction of complex molecular architectures, offering chemists a versatile and reactive handle for cross-coupling and further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing functionalized indole cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require halogenated indole structures.
• Material Science: Serves as a precursor for organic semiconductors, dyes, and photochromic materials due to its electron-rich indole system and halogen substituent.
• Cross-Coupling Reactions: The iodine atom at the 3-position makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the exploration of new chemical space in drug discovery programs.
• Academic Research: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	n-Boc-3-Iodo-7-Methyl-Indole
CAS No.	914349-35-2
Molecular Formula	C₁₄H₁₆INO₂
Molecular Weight	357.19 g/mol
Synonyms	1-Boc-3-iodo-7-methylindole; tert-Butyl 3-iodo-7-methyl-1H-indole-1-carboxylate; 3-Iodo-7-methyl-1H-indole-1-carboxylic acid tert-butyl ester; 3-Iodo-7-methyl-1-(tert-butoxycarbonyl)indole; N-Boc-3-iodo-7-methylindole; 7-Methyl-3-iodo-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-iodo-7-methylindole
EINECS	Contact for details

Quality Control

Our n-Boc-3-Iodo-7-Methyl-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.