Description

1-Boc-3-Bromo-4-Chloroindole is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of protective and halogen functional groups, enabling precise and efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides by serving as a core heterocyclic scaffold.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Academic & R&D: Employed in methodological studies and as a standard reagent for exploring new palladium-catalyzed cross-coupling reactions.
• Peptidomimetics: Useful for incorporating the indole moiety into peptide backbones to modulate biological activity and stability.

Basic Information

Product Name	1-Boc-3-Bromo-4-Chloroindole
CAS No.	914349-33-0
Molecular Formula	C₁₃H₁₃BrClNO₂
Molecular Weight	330.60 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-bromo-4-chloro-1H-indole; tert-Butyl 3-bromo-4-chloro-1H-indole-1-carboxylate; 3-Bromo-4-chloro-1H-indole-1-carboxylic acid tert-butyl ester; 3-Bromo-4-chloro-1-((tert-butoxy)carbonyl)-1H-indole; 1-Boc-3-bromo-4-chloroindole; Boc-3-Br-4-Cl-indole; 914349-33-0
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Bromo-4-Chloroindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.