Description

1-Boc-5-Benzyloxy-3-Bromoindole is a high-purity, multi-functional indole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic protection of the indole nitrogen with a Boc group and the 5-position with a benzyloxy group, while presenting a reactive bromine atom at the 3-position for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its bioactive indole core.
• Chemical Synthesis: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create diverse indole libraries.
• Material Science: Potential monomer or intermediate for synthesizing specialized organic electronic materials and dyes.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	1-Boc-5-Benzyloxy-3-Bromoindole
CAS No.	914349-28-3
Molecular Formula	C20H20BrNO3
Molecular Weight	402.28 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-(benzyloxy)-3-bromoindole; 3-Bromo-5-benzyloxy-1-Boc-indole; tert-Butyl 5-(benzyloxy)-3-bromo-1H-indole-1-carboxylate; 5-Benzyloxy-3-bromo-1-Boc-indole; 1-Boc-5-benzyloxy-3-bromoindole; 3-Bromo-1-Boc-5-benzyloxyindole; 1-Boc-3-bromo-5-(phenylmethoxy)-1H-indole
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Benzyloxy-3-Bromoindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material consistency, supporting your critical research and development timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.