Description

1-Boc-3,5-Dibromoindole is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel drug candidates, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of biologically active indole-based compounds, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Material Science: Serves as a monomer or functional unit in the creation of advanced polymers and organic electronic materials.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and the exploration of new synthetic pathways.
• Peptidomimetics: Facilitates the incorporation of modified tryptophan analogs into peptide chains for drug discovery.
• Cross-Coupling Reactions: The dibromo substitution pattern makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create diverse molecular libraries.

Basic Information

Product Name	1-Boc-3,5-Dibromoindole
CAS No.	914349-23-8
Molecular Formula	C₁₃H₁₃Br₂NO₂
Molecular Weight	383.06 g/mol
Synonyms	tert-Butyl 3,5-dibromo-1H-indole-1-carboxylate; 3,5-Dibromo-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3,5-dibromoindole; Boc-3,5-Dibromoindole; N-Boc-3,5-dibromoindole; 3,5-Dibromo-N-Boc-indole; 1-Boc-3,5-dibromo-1H-indole
EINECS	Contact for details

Quality Control

Our 1-Boc-3,5-Dibromoindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.