Description

1-Boc-7-Benzyloxy-3-Hydroxymethylindole is a high-purity, protected indole derivative serving as a critical advanced intermediate in modern organic synthesis. This compound is essential for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and pest management solutions.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds and specialty chemicals.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new synthetic pathways.
• Peptidomimetic & Bioconjugate Chemistry: The protected hydroxymethyl and indole functionalities make it suitable for constructing peptide analogs and bioconjugates.

Basic Information

Product Name	1-Boc-7-Benzyloxy-3-Hydroxymethylindole
CAS No.	914349-16-9
Molecular Formula	C21H23NO4
Molecular Weight	353.41 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-7-(benzyloxy)-3-(hydroxymethyl)-1H-indole; 3-(Hydroxymethyl)-7-(phenylmethoxy)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 7-(benzyloxy)-3-(hydroxymethyl)-1H-indole-1-carboxylate; 1-Boc-7-OBn-3-CH2OH-indole; Boc-7-Benzyloxyindole-3-methanol; 914349-16-9
EINECS	Contact for details

Quality Control

Our 1-Boc-7-Benzyloxy-3-Hydroxymethylindole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single impurity	≤1.0%
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.