Description

1-Boc-5-Benzyloxy-3-Hydroxymethylindole is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for constructing complex molecular architectures, offering chemists a versatile building block with orthogonal protecting groups. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and CNS research.
• Peptidomimetics & Bioconjugation: Used to incorporate indole-based scaffolds into peptides or for labeling biomolecules.
• Agrochemical Research: Serves as a building block for developing new crop protection agents and herbicides.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Academic & R&D Laboratories: Employed in methodological studies and the exploration of new synthetic pathways in organic chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing tailored compounds for client projects.

Basic Information

Product Name	1-Boc-5-Benzyloxy-3-Hydroxymethylindole
CAS No.	914349-14-7
Molecular Formula	C21H23NO4
Molecular Weight	353.41 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-5-(benzyloxy)-3-(hydroxymethyl)-1H-indole; tert-Butyl 5-(benzyloxy)-3-(hydroxymethyl)-1H-indole-1-carboxylate; 1-Boc-5-BnO-3-CH2OH-indole; 5-Benzyloxy-3-hydroxymethylindole-1-carboxylic acid tert-butyl ester; N-Boc-5-benzyloxy-3-hydroxymethylindole; 1H-Indole-1-carboxylic acid, 5-(phenylmethoxy)-3-(hydroxymethyl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Benzyloxy-3-Hydroxymethylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.