Description

1-Boc-5-Cyano-3-Hydroxymethylindole is a high-value, multifunctional indole derivative serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a Boc-protected amine and a hydroxymethyl group, makes it an indispensable precursor for constructing complex pharmaceutical intermediates and bioactive molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Peptidomimetics & PROTACs: Serves as a core structural element in the design of peptide mimics and Proteolysis-Targeting Chimeras.
• Material Science Research: Employed in the synthesis of functional organic materials and dyes.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services.

Basic Information

Product Name	1-Boc-5-Cyano-3-Hydroxymethylindole
CAS No.	914349-11-4
Molecular Formula	C15H16N2O3
Molecular Weight	272.30 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-cyano-3-(hydroxymethyl)indole; tert-Butyl 5-cyano-3-(hydroxymethyl)-1H-indole-1-carboxylate; 5-Cyano-3-hydroxymethylindole-1-carboxylic acid tert-butyl ester; 1-Boc-5-cyanoindole-3-methanol; Boc-5-CN-3-CH2OH-indole; N-Boc-5-cyano-3-hydroxymethylindole
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Cyano-3-Hydroxymethylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.