Description

1-Boc-3-Hydroxymethyl-6-Methoxyindole is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the efficient construction of complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of indole-based drug candidates, including kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in combinatorial chemistry and parallel synthesis libraries for structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Serves as a scaffold for constructing peptide-like molecules with enhanced metabolic stability.
• Agrochemical Development: Employed in the research and production of novel herbicides and plant growth regulators.
• Material Science Precursor: Potential building block for functional organic materials and dyes.
• Academic & Contract Research: Used in university and CRO laboratories for method development and novel synthetic route exploration.

Basic Information

Product Name	1-Boc-3-Hydroxymethyl-6-Methoxyindole
CAS No.	914349-08-9
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-3-(hydroxymethyl)-6-methoxyindole; tert-Butyl 3-(hydroxymethyl)-6-methoxy-1H-indole-1-carboxylate; 6-Methoxy-1H-indole-3-methanol, 1-(1,1-dimethylethyl) 1,1-dimethylethyl ester; 1-Boc-6-methoxyindole-3-methanol; 3-(Hydroxymethyl)-6-methoxy-1H-indole-1-carboxylic acid tert-butyl ester; Boc-6-methoxy-3-indolemethanol; 914349-08-9
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Hydroxymethyl-6-Methoxyindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.