Description

n-Hydroxy-5-Chloro-1H-Indole-3-Carboxamidine is a specialized indole derivative with a reactive amidoxime functional group. This compound serves as a versatile and high-value synthetic intermediate, particularly in the development of novel pharmaceutical agents and bioactive molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probe: Utilized in research to study biological pathways and protein interactions due to its metal-chelating amidoxime group.
• Fine Chemical Synthesis: Intermediate for creating complex molecules used in material science, dyes, and advanced organic synthesis.
• Academic & Contract Research: Serves as a starting material for methodological development and discovery chemistry in academic and CRO laboratories.

Basic Information

Product Name	n-Hydroxy-5-Chloro-1H-Indole-3-Carboxamidine
CAS No.	914349-02-3
Molecular Formula	C9H8ClN3O
Molecular Weight	209.63 g/mol
Synonyms	5-Chloro-1H-indole-3-carboximidamide, N-hydroxy-; 5-Chloro-N-hydroxy-1H-indole-3-carboxamidine; 5-Chloro-1H-indole-3-carboxamidoxime; 3-(N-Hydroxyamidino)-5-chloroindole; 914349-02-3; 5-Chloroindole-3-amidoxime; N-Hydroxy-5-chloroindole-3-carboxamidine
EINECS	Contact for details

Quality Control

Our n-Hydroxy-5-Chloro-1H-Indole-3-Carboxamidine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.