Description

1-Boc-5-Benzyloxy-3-Formylindole is a high-purity, multi-functional indole derivative used as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic protection of the indole nitrogen with the Boc group and the presence of both a benzyl-protected phenol and a reactive formyl group, enabling precise, sequential functionalization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel indole-based drug candidates, including kinase inhibitors and serotonin receptor modulators.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage the indole scaffold for biological activity.
• Organic Synthesis: Serves as a versatile precursor for constructing complex molecular architectures via reactions at the formyl group, such as condensations, reductions, and nucleophilic additions.
• Material Science: Potential monomer or intermediate for creating specialized polymers and organic electronic materials with unique optoelectronic properties.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	1-Boc-5-Benzyloxy-3-Formylindole
CAS No.	914348-98-4
Molecular Formula	C21H21NO4
Molecular Weight	351.40 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-5-(benzyloxy)-1H-indole-3-carboxaldehyde; tert-Butyl 5-(benzyloxy)-3-formyl-1H-indole-1-carboxylate; 5-Benzyloxy-1-Boc-indole-3-carboxaldehyde; 1-Boc-5-benzyloxyindole-3-carboxaldehyde; 1-Boc-5-O-benzyl-3-formylindole; 1-Boc-5-(benzyloxy)indole-3-carbaldehyde; 1-Boc-5-benzyloxy-3-formyl-1H-indole; 5-(Benzyloxy)-1-[(2-methylpropan-2-yl)oxycarbonyl]-1H-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Benzyloxy-3-Formylindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.