Description

1-Boc-7-Methyl-3-Formylindole is a high-purity, advanced pharmaceutical intermediate featuring a protected indole scaffold. This compound is specifically engineered for use in complex multi-step organic syntheses, offering a critical building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Academic Research: Employed in university and institutional labs for methodological development and the study of heterocyclic chemistry.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	1-Boc-7-Methyl-3-Formylindole
CAS No.	914348-96-2
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-7-methyl-1H-indole-3-carboxaldehyde; tert-Butyl 7-methyl-3-formyl-1H-indole-1-carboxylate; 7-Methyl-1H-indole-3-carboxaldehyde, 1-(1,1-dimethylethyl) 1,1-dimethyl ester; 1-Boc-7-methylindole-3-carboxaldehyde; 1-Boc-7-methyl-3-carbaldehyde indole; N-Boc-7-methyl-3-formylindole; tert-Butyl 7-methyl-3-formylindole-1-carboxylate; 1-(tert-Butoxycarbonyl)-7-methyl-1H-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-Boc-7-Methyl-3-Formylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.