Description

1-Boc-6-Methyl-3-Formylindole is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) due to its reactive aldehyde and protected amine functionalities.
• Peptidomimetic Synthesis: Serves as a core structure for creating indole-based peptidomimetics and constrained analogs.
• Agrochemical Development: Intermediate in the synthesis of advanced crop protection agents and plant growth regulators.
• Material Science Precursor: Potential starting material for the development of organic electronic materials and functional dyes.
• Academic & Contract Research: Used in university laboratories and CROs (Contract Research Organizations) for method development and novel compound library generation.

Basic Information

Product Name	1-Boc-6-Methyl-3-Formylindole
CAS No.	914348-95-1
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-6-methyl-1H-indole-3-carboxaldehyde; 6-Methyl-1-Boc-indole-3-carboxaldehyde; tert-Butyl 6-methyl-3-formyl-1H-indole-1-carboxylate; 1-Boc-6-methylindole-3-carbaldehyde; N-Boc-6-methyl-3-formylindole; 1-Boc-6-methyl-1H-indole-3-carbaldehyde; 914348-95-1; tert-Butyl (6-methyl-3-formyl-1H-indol-1-yl)carboxylate
EINECS	Contact for details

Quality Control

Our 1-Boc-6-Methyl-3-Formylindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable, and our quality control protocols are designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.