Description

1-Boc-5-Methyl-3-Formylindole is a high-purity, advanced pharmaceutical intermediate featuring a protected indole scaffold with formyl and methyl substituents. This compound is critical for medicinal chemistry research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the production of novel drug candidates and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel indole-based drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its reactive formyl group and protected amine.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic systems via reactions such as reductive amination, condensation, and cross-coupling.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and plant growth regulators.
• Academic & Industrial R&D: Essential for chemical libraries and high-throughput screening in both academic institutions and corporate discovery programs.

Basic Information

Product Name	1-Boc-5-Methyl-3-Formylindole
CAS No.	914348-94-0
Molecular Formula	C15H17NO3
Molecular Weight	259.30 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-5-methyl-1H-indole-3-carboxaldehyde; tert-Butyl 5-methyl-3-formyl-1H-indole-1-carboxylate; 5-Methyl-1H-indole-3-carboxaldehyde, 1-(1,1-dimethylethyl) ester; 1-Boc-5-methylindole-3-carboxaldehyde; 1-Boc-5-methyl-3-formyl-1H-indole; 1-(tert-Butoxycarbonyl)-5-methyl-1H-indole-3-carbaldehyde; 914348-94-0; Boc-5-Me-3-CHO-indole
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Methyl-3-Formylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.