Description

1-Boc-5-Cyano-3-Formylindole is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive formyl and cyano groups, protected by a Boc group, which allows for selective and sequential functionalization under mild conditions. It is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly kinase inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides with indole core structures.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors and advanced polymeric materials.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including palladium-catalyzed cross-couplings and multi-component reactions.
• Peptidomimetics & Bio-conjugation: The reactive aldehyde group facilitates its use in creating peptide analogs and bioconjugate linkers for diagnostic applications.

Basic Information

Product Name	1-Boc-5-Cyano-3-Formylindole
CAS No.	914348-93-9
Molecular Formula	C15H14N2O3
Molecular Weight	270.29 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-5-cyano-1H-indole-3-carboxaldehyde; 5-Cyano-3-formyl-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 5-cyano-3-formyl-1H-indole-1-carboxylate; 1-Boc-5-cyanoindole-3-carboxaldehyde; 1-Boc-5-cyanoindole-3-carbaldehyde; 1-(tert-Butoxycarbonyl)-5-cyanoindole-3-carboxaldehyde; 5-Cyano-1H-indole-3-carboxaldehyde, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Cyano-3-Formylindole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain reliability and documentation transparency supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.