Description

2-[4-Nitro-2-(Trifluoromethyl)Phenyl]-1,2,3,4-Tetrahydro Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular structure. This compound is of significant commercial value for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring a tetrahydroisoquinoline scaffold.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the nitro and trifluoromethyl groups can contribute to biological activity.
• Organic Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science: Potential application in the synthesis of specialty polymers or organic electronic materials due to its aromatic and electron-withdrawing functional groups.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, method development, and quality control in regulatory and R&D settings.

Basic Information

Product Name	2-[4-Nitro-2-(Trifluoromethyl)Phenyl]-1,2,3,4-Tetrahydro Isoquinoline
CAS No.	914348-89-3
Molecular Formula	C₁₆H₁₃F₃N₂O₂
Molecular Weight	322.29 g/mol
Synonyms	2-(4-Nitro-2-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-2-[4-nitro-2-(trifluoromethyl)phenyl]isoquinoline; 2-(4-Nitro-2-trifluoromethylphenyl)-1,2,3,4-tetrahydroisoquinoline; 914348-89-3; 2-(4-Nitro-2-(trifluoromethyl)phenyl)-3,4-dihydro-1H-isoquinoline
EINECS	Contact for details

Quality Control

Our 2-[4-Nitro-2-(Trifluoromethyl)Phenyl]-1,2,3,4-Tetrahydro Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.