Description

4-(3,4-Dihydro-1H-Isoquinolin-2-Yl)-3-Trifluoromethyl Phenylamine is a high-value, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines an isoquinoline moiety with a trifluoromethyl-substituted aniline. This compound is critical for the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It serves as a key building block for pharmaceutical companies and research institutions focused on developing new therapeutic agents, especially in areas like central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• CNS Drug Development: Serves as a building block for compounds targeting neurological and psychiatric conditions.
• Oncology Research: Employed in the development of potential small-molecule inhibitors and targeted cancer therapies.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents with novel modes of action.
• Material Science: Can be utilized in the development of specialty chemicals and advanced organic materials.

Basic Information

Product Name	4-(3,4-Dihydro-1H-Isoquinolin-2-Yl)-3-Trifluoromethyl Phenylamine
CAS No.	914348-87-1
Molecular Formula	C16H15F3N2
Molecular Weight	292.30 g/mol
Synonyms	3-Trifluoromethyl-4-(1,2,3,4-tetrahydroisoquinolin-2-yl)aniline; 4-(3,4-Dihydro-1H-isoquinolin-2-yl)-3-(trifluoromethyl)aniline; 2-[2-Amino-5-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydroisoquinoline; 4-(1,2,3,4-Tetrahydroisoquinolin-2-yl)-3-(trifluoromethyl)benzenamine; 3-(Trifluoromethyl)-4-(3,4-dihydro-1H-isoquinolin-2-yl)phenylamine
EINECS	Contact for details

Quality Control

Our 4-(3,4-Dihydro-1H-Isoquinolin-2-Yl)-3-Trifluoromethyl Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.