Description

5-Bromo-2-(Pyrrolidin-3-Yloxy)Pyrimidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, particularly in constructing complex heterocyclic scaffolds with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides and fungicides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	5-Bromo-2-(Pyrrolidin-3-Yloxy)Pyrimidine
CAS No.	914347-82-3
Molecular Formula	C8H10BrN3O
Molecular Weight	244.09 g/mol
Synonyms	5-Bromo-2-[(3-pyrrolidinyl)oxy]pyrimidine; 2-[(Pyrrolidin-3-yl)oxy]-5-bromopyrimidine; 5-Bromo-2-(3-pyrrolidinyloxy)pyrimidine; Pyrimidine, 5-bromo-2-(3-pyrrolidinyloxy)-; 914347-82-3
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Pyrrolidin-3-Yloxy)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.