Description

3-Amino-5-Cyanophenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both an amino and a cyano group on the phenyl ring, makes it a versatile intermediate for constructing complex molecules via Suzuki-Miyaura cross-coupling and other boronic acid-mediated reactions. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific aromatic frameworks.
• Material Science: Building block for creating functionalized polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: Essential boronic acid component for forming carbon-carbon bonds in complex organic synthesis.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and sensors for biological target identification.
• Ligand Synthesis: Intermediate for preparing specialized ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	3-Amino-5-Cyanophenylboronic Acid
CAS No.	913943-05-2
Molecular Formula	C7H7BN2O2
Molecular Weight	161.96 g/mol
Synonyms	(3-Amino-5-cyanophenyl)boronic acid; 3-Cyano-5-aminophenylboronic acid; 5-Cyano-3-aminobenzeneboronic acid; Boronic acid, B-(3-amino-5-cyanophenyl)-; 3-Amino-5-cyanobenzeneboronic acid; 913943-05-2; 3-Amino-5-cyanophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Cyanophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.