Description

1-Boc-4-Nitroindole is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the efficient construction of complex nitrogen-containing heterocycles, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and CNS disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore novel bioactive molecules.
• Agrochemical Synthesis: Serves as a building block for developing new pesticides and herbicides with specific modes of action.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & Institutional R&D: A valuable reagent for methodological development and teaching advanced synthetic organic chemistry techniques.
• Peptidomimetic & Bioconjugate Chemistry: Facilitates the introduction of nitro-functionalized indole scaffolds into peptide backbones or biomolecule conjugates.

Basic Information

Product Name	1-Boc-4-Nitroindole
CAS No.	913836-24-5
Molecular Formula	C₁₃H₁₄N₂O₄
Molecular Weight	262.26 g/mol
Synonyms	1-[(tert-Butoxy)carbonyl]-4-nitro-1H-indole; 4-Nitro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-nitro-1H-indole-1-carboxylate; 1-Boc-4-nitroindole; Boc-4-Nitroindole; 4-Nitroindole-1-carboxylic acid tert-butyl ester; 1H-Indole-1-carboxylic acid, 4-nitro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Nitroindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.