Description

3-Carboxy-4-Chlorobenzeneboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a carboxylic acid and a boronic acid group, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions to create novel biaryl compounds.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its ability to introduce the chlorophenyl moiety into complex molecules.
• Ligand for Catalysis: Can be utilized to prepare specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Material Science Building Block: Employed in the creation of organic electronic materials, such as those for OLEDs and organic semiconductors, due to its conjugated system and functional handles.
• Bioconjugation & Probe Development: The boronic acid group allows for conjugation with diols, making it useful in developing sensors, diagnostic probes, and targeted drug delivery systems.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new carbon-carbon bond-forming methodologies and synthesizing complex natural product analogs.

Basic Information

Product Name	3-Carboxy-4-Chlorobenzeneboronic Acid
CAS No.	913835-32-2
Molecular Formula	C7H6BClO4
Molecular Weight	200.38 g/mol
Synonyms	(3-Carboxy-4-chlorophenyl)boronic acid; 4-Chloro-3-carboxyphenylboronic acid; 2-Chloro-5-boronobenzoic acid; Benzoic acid, 4-chloro-3-borono-; 3-Borono-4-chlorobenzoic acid; 4-Chloro-3-(dihydroxyboryl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Carboxy-4-Chlorobenzeneboronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal screening, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.