Description

4-Ethynylthiophene-2-Carbaldehyde is a high-value, multi-functional organic building block featuring both an aldehyde and an ethynyl group on a thiophene scaffold. This unique molecular architecture makes it a critical intermediate for synthesizing advanced materials and complex pharmaceutical agents. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and organic electronics sectors for constructing novel conjugated systems and heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Organic Semiconductor Precursor: Used in the synthesis of conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Agrochemical Synthesis: Serves as a building block for creating new active ingredients with enhanced properties.
• Ligand and Catalyst Development: The aldehyde and alkyne functionalities allow for the creation of complex chelating ligands for catalysis.
• Material Science Research: Employed in developing advanced polymers, dyes, and sensors with tailored electronic properties.
• Click Chemistry Substrate: The terminal alkyne group is ideal for Huisgen cycloaddition (click) reactions to create diverse molecular libraries.

Basic Information

Product Name	4-Ethynylthiophene-2-Carbaldehyde
CAS No.	913828-75-8
Molecular Formula	C7H4OS
Molecular Weight	136.17 g/mol
Synonyms	2-Formyl-4-ethynylthiophene; 4-Ethynyl-2-thiophenecarboxaldehyde; 4-Ethynylthiophene-2-carboxaldehyde; Thiophene-2-carboxaldehyde, 4-ethynyl-; 4-Ethynyl-2-formylthiophene
EINECS	Contact for details

Quality Control

Our 4-Ethynylthiophene-2-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant industry standards, and custom purity grades or analytical data packages can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the certificate of analysis. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.