Description

4'-Fluoro-Spiro[Cyclopropane-1,3'-[3H]Indol]-2'(1'H)-One is a high-value, structurally complex organic compound featuring a spirocyclic indole scaffold with a fluorine substituent. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry, enabling the development of novel bioactive molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential herbicidal or insecticidal properties.
• Organic Synthesis Building Block: Utilized in complex organic transformations, including cross-coupling reactions and cycloadditions, to create novel chemical entities.
• Material Science Research: Investigated as a component for developing specialty polymers or organic electronic materials due to its unique fused-ring structure.

Basic Information

Product Name	4'-Fluoro-Spiro[Cyclopropane-1,3'-[3H]Indol]-2'(1'H)-One
CAS No.	913720-11-3
Molecular Formula	C₁₀H₈FNO
Molecular Weight	177.18 g/mol
Synonyms	4'-Fluoro-1'H-spiro[cyclopropane-1,3'-indol]-2'-one; 4'-Fluoro-1'H-spiro[cyclopropane-1,3'-indole]-2'(3'H)-one; 4'-Fluoro-1'H-spiro[cyclopropane-1,3'-indol]-2'-one; 4'-Fluoro-spiro[cyclopropane-1,3'-indolin]-2-one; 913720-11-3; Spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one, 4'-fluoro-; 4'-Fluoro-1'H-spiro[cyclopropane-1,3'-indole]-2'-one
EINECS	Contact for details

Quality Control

Our production of 4'-Fluoro-Spiro[Cyclopropane-1,3'-[3H]Indol]-2'(1'H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.