Description

1H-Indole-1-Carboxylic Acid, 2-Borono-5-[(Dimethylamino)Methyl]-, 1-(1,1-Dimethylethyl) Ester is a sophisticated boronic acid ester derivative of indole, designed for advanced synthetic applications. This compound matters as a key building block in modern pharmaceutical and agrochemical research, enabling the construction of complex molecules through versatile cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and CNS (Central Nervous System) research.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester partner for constructing biaryl and heterobiaryl scaffolds essential in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with targeted modes of action.
• Material Science & OLED Development: Acts as a building block for creating organic semiconductors and emissive layers in electronic devices.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Process Chemistry & Scale-up: Employed in the optimization and pilot-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-5-[(Dimethylamino)Methyl]-, 1-(1,1-Dimethylethyl) Ester
CAS No.	913388-74-6
Molecular Formula	C17H25BN2O4
Molecular Weight	332.21 g/mol
Synonyms	tert-Butyl 2-borono-5-[(dimethylamino)methyl]-1H-indole-1-carboxylate; 5-[(Dimethylamino)methyl]-1H-indole-1-carboxylic Acid 2-Boronic Acid 1-(1,1-Dimethylethyl) Ester; 2-Borono-5-[(dimethylamino)methyl]-1H-indole-1-carboxylic Acid tert-Butyl Ester; Boronic Acid Ester Indole Derivative; BOC-Protected Indole Boronate Ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 2-Borono-5-[(Dimethylamino)Methyl]-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.